de
en
PRE-IMPLANTATION GENETIC DIAGNOSIS

"Detecting genetic defects"

Eliminating the transmission of genetic abnormalities and diseases as far as possible.

Pre-implantation genetic diagnosis for us

PGT (Pre-Implantation Genetic Testing) genetic analysis - where offered and legally permissible - can make sense for couples with predisposing genetic factors, e.g. if there is a genetic disease in the family. As part of an extensive consultation and analysis of the individual situation, our team of physicians will determine the extent of the application with the couple according to the specific findings. The objectives are always to avoid the transfer of genetic diseases as far as possible and to increase the chances of giving birth to a healthy child.

 

Possible indications:


Couples with hereditary genetic diseases: Monogenetic diseases, X chromosome-linked diseases, chromosomal abnormalities
Couples, who have suffered repeated miscarriages
Couples with previous but unsuccessful IVF treatments
Women over 35, to examine the risk of chromosome abnormalities

Pre-implantation genetic diagnosis is conducted during a cycle of in-vitro fertilisation and allows for the retrieval of cell material from an unfertilised or fertilised egg before transferring it to the uterus and for it to be examined for possible genetic disorders.

 

PGT-A (Preimplantation Genetic Testing for aneuploidy)

A deviation from the normal number of chromosomes, i.e. individual chromosomes are surplus or absent; aneuploidy is a common cause of miscarriages. There are many types of chromosomal abnormalities, which are divided into numerical and structural. Numerical abnormalities indicate a chromosome more or a chromosome less than in the case of a normal set of chromosomes. A structural abnormality is when a part of a specific chromosome is missing, surplus or was transferred to another chromosome.

The PGT-A technique is used to identify numerical chromosomal abnormalities in embryos. The normal number of chromosomes is 23 pairs. One of the most frequent numerical abnormalities, known as down syndrome, can occur if there are three sets of chromosome no. 21 (trisomy 21).

 

PGT-M (Pre-implantation Genetic Testing for monogenic diseases)

Monosomies are genetic diseases that can be caused by the mutation or change of a DNA sequence of one single gene and passed on to offspring. The PGT-M procedure is a reliable method for families with hereditary conditions that aims to eliminate the transmission of genetic defects and diseases to the embryo as far as possible.

fertipedia

 

Technical terms explained quickly

From Amenorrhea to Zygote: Here you will find an overview of medical terms and their explanations.

 

Medithek

 
Play
Play
Play